The Dynamical ISM Across Time and Spatial Scales, held September 26th to 30th 2022 in Puerto Varas, Chile, continued the series of conferences on the dense interstellar medium, its physics and chemistry, and its relation to star formation. The Symposium brought together about 135 scientists from 17 countries. With 74 talks (7 reviews, 29 invited, and 38 contributed talks) and 56 posters. The material compiled in these proceedings provide a good summary and overview of the state of the field and the upcoming perspectives, and a valuable benchmark just before new facilities like CCAT-prime come online.